Non-GMO | Gluten Free| 90 Vegetarian Capsules NPN 80023078
Beautiful Legs Formula
Helps treat varicose veins and chronic venous insufficiency
- Used in herbal medicine to help treat varicose veins and chronic venous insufficiency
- Helps relieve pain, swelling, and cramps due to vein insufficiency
- Improves the appearance of varicose and spider veins
- Eases fluid retention to alleviate pressure in the legs
- Provides the antioxidants diosmin and hesperidin
- Formulated for vein health and circulation
VeinSense beautiful legs formula combines the natural citrus bioflavonoids, diosmin and hesperidin, with horse chestnut and butcher’s broom extracts to provide supportive therapy for varicose veins and chronic venous insufficiency (CVI). This non-GMO, gluten-free supplement relieves symptoms of pain, swelling, and leg cramps by easing fluid retention and encouraging healthy vein structure.
Recommended Adult Dose: 1 capsule 3 times daily preferably with meals or as directed by a health care practitioner.
CVI affects 20–25% of women, with symptoms ranging from the development of varicose veins to leg pain, itching, cramping, and the feeling of “heavy legs” (Pittler & Ernst, 2012; Santler & Goerge, 2017). Underlying contributors of CVI include inflammation of blood vessel walls and a reduced ability of the veins to circulate blood efficiently, causing it to pool in the legs (Santler & Goerge, 2017). Women become more susceptible to CVI in older age. Without treatment, small varicose veins can become enlarged and more visible over time (Santler & Goerge, 2017).
Diosmin and hesperidin are citrus flavonoids with anti-inflammatory and antioxidant activities that promote vein health. Diosmin is one of the most popular natural therapies for CVI due to its effectiveness in scavenging free radicals and reducing oxidative stress in the body (Feldo et al., 2018). Its effect was observed in a study of CVI patients who showed a 40% reduction in the inflammatory biomarker isoprostane after they took 600 mg of diosmin twice per day for three months (Feldo et al., 2018).
Diosmin is commonly paired with hesperidin, and a 9:1 ratio of these flavonoids has been used successfully to improve microcirculation and normalize oxidative processes in CVI patients (Beyaz & Ata, 2021). In a five-month prospective study, patients diagnosed with venous insufficiency supplemented with 900 mg of diosmin and 100 mg of hesperidin per day in addition to wearing low-pressure venous compression stockings. At the beginning of treatment, all patients were experiencing saphenofemoral junctional reflux (SFJ), the reflux of blood back down the leg veins. A Doppler examination revealed that the combined therapy reduced the number of patients with SFJ by 66% and may have contributed to the structural recovery of their veins. With recovery, patients also experienced reductions in symptoms of pain, swelling, and itching (Beyaz & Ata, 2021).
Horse chestnut (Aesculus hippocastanum) has a long history of use for leg cramps and hemorrhoids. It continues to be used today throughout Europe and North America for CVI and post-operative edema (Thorne Research, 2009). Horse chestnut seeds are most recognized for their active compound aescin, which has anti-inflammatory activities and is used to reduce leg swelling, improve vein tone, and increase circulation (Dudek-Makuch & Studzin´ska-Sroka, 2015).
A review of 17 randomized controlled trials concluded that horse chestnut extracts provide significant relief from CVI symptoms, including leg pain, edema, and itching after 2–16 weeks of supplementation (Pittler & Ernst, 2012). Doses of 100 mg of escin per day were also shown to reduce the leg volume of CVI patients after two weeks, while other studies observed that horse chestnut may be as effective as wearing compression stockings for improving circulation and relieving fluid retention (Pittler & Ernst, 2012).
Butcher’s broom (Ruscus aculeatus L.) is an herbal diuretic that has been used to treat circulatory problems for at least 2,000 years. The German Commission E now classifies its rhizome extracts as herbal edema protectants that have been used successfully to improve the swelling, itching, cramping, and varicose veins associated with CVI (Engels, 2010; Thorne Research, 2001). The saponins found in butcher’s broom rhizomes are believed to have anti-inflammatory activities and improve lymphatic drainage and circulation (Engels, 2010; Thorne Research, 2001).
Each Vegetarian Capsule Contains
|Diosmin (Citrus sinensis) (peel)||300 mg|
Horse Chestnut Extract (Aesculus hippocastanum, 18% escin) (seed)
|Butcher’s Broom Extract (Ruscus aculeatus, 10% ruscogenins) (rhizome)||33 mg|
|Hesperidin (Citrus sinensis) (fruit)||33 mg|
Microcrystalline cellulose, vegetarian capsule (cellulose, purified water, silica), vegetable grade magnesium stearate (lubricant).
Beyaz, M.O., & Ata, E.C. (2021). Effects of diosmin-hesperidin and low pressure compression stocking combination in superficial venous insufficiency. Ann Med Res, 28(1), 132-5.
Dudek-Makuch, M., & Studzin´ska-Sroka, E. (2015). Horse chestnut – efficacy and safety in chronic venous insufficiency: an overview. Rev Bras Farmacogn, 25, 533-41.
Engels, G. (2010). Butcher’s Broom Ruscus aculeatus Ruscaceae. HerbalGram, (85), 1-4.
Feldo, M., Woźniak, M., Wójciak-Kosior, M., et al. (2018). Influence of diosmin treatment on the level of oxidative stress markers in patients with chronic venous insufficiency. Oxid Med Cell Longev, 2018, 2561705.
Pittler, M.H., & Ernst, E. (2012). Horse-chestnut seed extract for chronic venous insufficiency. Cochrane Database Syst Rev, 11(11), CD003230.
Santler, B., & Goerge, T. (2017). Chronic venous insufficiency – a review of pathophysiology, diagnosis, and treatment. J Dtsch Dermatol Ges, 15(5), 538-56.
Thorne Research, Inc. (2001). Ruscus aculeatus (butcher’s broom). Monograph. Altern Med Rev, 6(6), 608-12.
Thorne Research, Inc. (2009). Aesculus hippocastanum (Horse chestnut). Monograph. Altern Med Rev, 14(3), 278-83.
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